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Title
Cranial edema associated with a protein-losing nephropathy in a golden-mantled flying fox (Pteropus pumilus)
Author(s)
Deem S.L., Heard D.J., Clippinger T.L., Buergelt C.D.
Published
1999
Publisher
Journal of Zoo and Wildlife Medicine
Abstract
An adult golden-mantled flying fox (Pteropus pumilus) was diagnosed with nephrotic syndrome on the basis of the findings of proteinuria, hypoalbuminemia, hypercholesterolemia, and cranial edema. Membranoproliferative glomerulitis and interstitial nephritis were confirmed antemortem by renal biopsy. The bat had received seven injections of oxytocin in the period immediately prior to presentation. The possible role of oxytocin in the development of the nephropathy is discussed. Supportive care and treatment with a single plasma transfusion, furosemide, and prednisone led to a gradual but complete resolution of the nephrotic syndrome in this animal. Copyright 1999 by American Association of Zoo Veterinarians.
Keywords
diuretic agent; furosemide; glucocorticoid; oxytocin; prednisone; animal; animal disease; article; bat; blood; blood analysis; blood examination; blood transfusion; case report; differential diagnosis; edema; female; kidney; liver; nephrotic syndrome; pathology; skull; Animals; Blood Chemical Analysis; Blood Transfusion; Chiroptera; Diagnosis, Differential; Diuretics; Edema; Female; Furosemide; Glucocorticoids; Hematologic Tests; Kidney; Liver; Nephrotic Syndrome; Oxytocin; Prednisone; Skull
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PUB12815