Title
Comparison of oral and intramuscular recombinant canine distemper vaccination in African Wild Dogs (Lycaon Pictus)
Author(s)
Connolly , M.;Thomas, P.;Woodroffe, R. Phil;Raphael, B.;;American Association of Zoo Veterinarians
Published
2013
Publisher
Journal of Zoo and Wildlife Medicine
Abstract
A series of three doses of recombinant canary-pox–vectored canine distemper virus vaccine was administered at 1-mo intervals, orally (n = 8) or intramuscularly (n = 13), to 21 previously unvaccinated juvenile African wild dogs (Lycaon pictus) at the Wildlife Conservation Society's Bronx Zoo. Titers were measured by serum neutralization at each vaccination and at intervals over a period of 3.5–21.5 mo after the initial vaccination. All postvaccination titers were negative for orally vaccinated animals at all sampling time points. Of the animals that received intramuscular vaccinations, 100% had presumed protective titers by the end of the course of vaccination, but only 50% of those sampled at 6.5 mo postvaccination had positive titers. None of the three animals sampled at 21.5 mo postvaccination had positive titers.

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PUB13597