Title
Use of a mycobacterium tuberculosis rapid lateral flow test for assessment of non-specific tuberculin responses in silvered langurs (trachypithecus cristatus ultima)
Author(s)
Georoff, T. A.;Calle, P. P.;McAloose, D.;Barrie, M. T.
Published
2010
Publisher
Journal of Zoo and Wildlife Medicine
Abstract
Nonspecific responses to intradermal tuberculin skin testing (TST) have been frequently documented in silvered langurs (Trachypithecus cristatus ultima) at the Wildlife Conservation Society's Bronx Zoo. A commercial rapid lateral flow immunoassay (RT) for the identification of Mycobacterium tuberculosis and M. bovis antibodies was employed to assess this test's correlation with TST results and tuberculosis status. Twenty-two silvered langurs were tested with both TST and RT. TST results were characterized into three groups as nonspecific tuberculin responses (n 9), responses to avian tuberculin only (n 6), or negative (n 7). Rapid lateral flow test results were negative in 20 of 22 individuals with equivocal results in two avian tuberculin responders. There was no difference in RT results between TST groups (P 0.178). Rapid lateral flow test results were not in agreement with mammalian old tuberculin TST results (κ 0.08) but showed raw agreement with tuberculosis status (proportion of overall agreement 0.909). Results suggest the RT assay may useful in the confirmation of nonspecific TST responders in silvered langurs. © 2010 American Association of Zoo Veterinarians.
Keywords
Langur;Nonspecific tuberculin response;TB testing;Trachypithecus;Tuberculin

Access Full Text

A full-text copy of this article may be available. Please email the WCS Library to request.



Back

PUB13819