Skip to main content
WCS
Menu
Library
Library Catalog
eJournals & eBooks
WCS Research
Archives
Research Use
Finding Aids
Digital Collections
WCS History
WCS Research
Research Publications
Science Data
Services for WCS Researchers
Archives Shop
Bronx Zoo
Department of Tropical Research
Browse By Product
About Us
FAQs
Intern or Volunteer
Staff
Donate
Search WCS.org
Search
search
Popular Search Terms
WCS History
Library and Archives
Library and Archives Menu
Library
Archives
WCS Research
Archives Shop
About Us
Donate
en
fr
Title
Genetic diversity and phylogeography of Jeju Orthohantavirus (Hantaviridae) in the Republic of Korea
Author(s)
Lee, S. H.;Kim, W. K.;Park, K.;...;Hwang, J.;et al.
Published
2020
Publisher
Virology
Published Version DOI
https://doi.org/10.1016/j.virol.2020.01.012
Abstract
Orthohantaviruses are negative-sense, single-stranded RNA viruses harbored by rodents, shrews, moles, and bats. Of the shrew-borne orthohantaviruses in the Republic of Korea (ROK), Jeju orthohantavirus (Jeju virus, JJUV) was found on Jeju Island. This small-scale epidemiologic survey investigated the geographic distribution and molecular phylogeny of JJUV in the ROK. In 32 trapping sites, tissues of 84 Crocidura shantungensis were analyzed for JJUV RNA. JJUV RNA was detected in seven (8.3%) shrews captured on the Korean peninsula. The molecular epidemiologic survey demonstrated the prevalence of JJUV by geographic distribution. The RNA loads of JJUV were evaluated in various tissues. Entire coding sequences of tripartite genomes were recovered from two JJUV strains on the mainland. Phylogenetic relationships of the JJUV revealed a distinct geographic lineage of mainland strains from the strains on Jeju Island. This study sheds light on the molecular epidemiology, phylogeographic diversity, and virus-host co-divergence of JJUV, ROK.
Keywords
Jeju orthohantavirus;Crocidura shantungensis;Korean peninsula;Epidemiologic survey;Phylogenetic analysis;white-toothed shrew;thottapalayam virus;sin-nombre;evolution;infection;sequence;mouse;east;Virology
Access Full Text
A full-text copy of this article may be available. Please email the
WCS Library
to request.
Back
PUB25127