Skip to main content
WCS
Menu
Library
Library Catalog
eJournals & eBooks
WCS Research
Archives
Research Use
Finding Aids
Digital Collections
WCS History
WCS Research
Research Publications
Science Data
Services for WCS Researchers
Archives Shop
Bronx Zoo
Department of Tropical Research
Browse By Product
About Us
FAQs
Intern or Volunteer
Staff
Donate
Search WCS.org
Search
search
Popular Search Terms
WCS History
Library and Archives
Library and Archives Menu
Library
Archives
WCS Research
Archives Shop
About Us
Donate
en
fr
Title
Predicting the potential for zoonotic transmission and host associations for novel viruses
Author(s)
Pandit, Pranav; Anthony, Simon; Goldstein, Tracey; Olival, Kevin; Doyle, Megan; Gardner, Nicole; Bird, Brian; Smith, Woutrina; Wolking, David; Gilardi, Kristen; Monagin, Corina; Kelly, Terra; Uhart, Marcela; Epstein, Jonathan; Machalaba, Catherine; Rostal, Melinda; Dawson, Patrick; Hagan, Emily; Sullivan, Ava; Li, Hongying; Chmura, Aleksei; Latinne, Alice; Lange, Christian; O'Rourke, Tammie; Olson, Sarah H.; Keatts, Lucy; Mendoza, A. Patricia; Perez, Alberto; Dejuste de Paula, Catia; Zimmerman, Dawn; Valitutto, Marc; LeBreton, Matthew; McIver, David; Islam, Ariful; Duong, Veasna; Mouiche, Moctar; Shi, Zheng-Li; Mulembakani, Prime; Kumakamba, Charles; Ali, Mohamed; Kebede, Nigatu; Tamoufe, Ubald; Bel-Nono, Samuel; Camara, Alpha; Pamungkas, Joko; Kalpy Coulibaly, Julien; Abu-Basha, Ehab; Kamau, Joseph; Silithammavong, Soubanh; Desmond, James; Hughes, Tom; Shiilegdamba, Enkhtuvshin; Aung, Ohnmar; Karmacharya, Dibesh; Nziza, Julius; Ndiaye, Daouda; Gbakima, Aiah; Sijali, Zikankuba; Wacharapluesadee, Supaporn; Robles, Erika Alandia; Ssebide, Benard; Suzan, Gerardo; Aguirre, Luis; Solorio, Monica; Dhole, Tapan; Hitchens, Peta; Joly, Damien; Saylors, Karen; Fine, Amanda; Murray, Suzan; Karesh, William; Daszak, Peter; Mazet, Jonna; PREDICT Consortium; Johnson, Christine
Published
Preprint
Publisher
Research Square
Published Version DOI
https://doi.org/10.21203/rs.3.rs-846253/v1
Abstract
Host-virus associations have co-evolved under ecological and evolutionary selection pressures that shape cross-species transmission and spillover to humans. Observed virus-host associations provide relevant context for newly discovered wildlife viruses to assess knowledge gaps in host range and estimate pathways for potential human infection. Using models to predict virus-host networks, we predicted the likelihood of humans as host for 513 newly discovered viruses detected by large scale wildlife surveillance at high-risk animal-human interfaces in Africa, Asia, and Latin America. Predictions indicated that novel coronaviruses are likely to infect a greater number of host species than viruses from other families. Our models further characterize novel viruses through prioritization scores and directly inform surveillance targets to identify host ranges for newly discovered viruses.
Access Full Text
A full-text copy of this article may be available. Please email the
WCS Library
to request.
Back
PUB27281